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Michael J. Clague

Researcher at University of Liverpool

Publications -  150
Citations -  23688

Michael J. Clague is an academic researcher from University of Liverpool. The author has contributed to research in topics: Endosome & Ubiquitin. The author has an hindex of 55, co-authored 145 publications receiving 20061 citations. Previous affiliations of Michael J. Clague include Humboldt University of Berlin & National Institutes of Health.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Breaking the chains: structure and function of the deubiquitinases.

David Komander, +2 more
- 01 Aug 2009 - 
TL;DR: DUBs are subject to multiple layers of regulation that modulate both their activity and their specificity, and due to their wide-ranging involvement in key regulatory processes, these enzymes might provide new therapeutic targets.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

Hannah E. J. Polson, +6 more
- 16 May 2010 - 
TL;DR: A role for WIPI2 in the progression of omegasomes into autophagosomes is proposed, which is thought to act as platforms forAutophagosome formation.