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José C. Fernández-Checa

Researcher at University of Southern California

Publications -  194
Citations -  21144

José C. Fernández-Checa is an academic researcher from University of Southern California. The author has contributed to research in topics: Mitochondrion & Oxidative stress. The author has an hindex of 69, co-authored 175 publications receiving 18337 citations. Previous affiliations of José C. Fernández-Checa include University of Barcelona & Spanish National Research Council.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Mitochondrial glutathione, a key survival antioxidant.

Montserrat Marí, +5 more
- 15 Oct 2009 - 
TL;DR: From the evaluation ofmGSH influence on different pathologic settings such as hypoxia, ischemia/reperfusion injury, aging, liver diseases, and neurologic disorders, it is becoming evident that it has an important role in the pathophysiology and biomedical strategies aimed to boost mGSH levels.
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Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species ROLE OF MITOCHONDRIAL GLUTATHIONE

Carmen García-Ruiz, +4 more
- 25 Apr 1997 - 
TL;DR: It is suggested that mitochondria are a target of ceramide produced in the signaling of TNF whose effect on mitochondrial electron transport chain leads to overproduction of hydrogen peroxide and consequently this phenomena may account for the generation of reactive oxygen species during TNF cytotoxicity.
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Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

Montserrat Marí, +8 more
- 01 Sep 2006 - 
TL;DR: A critical role is proposed for mitochondrial FC loading in precipitating SH, by sensitizing hepatocytes to TNF and Fas through mGSH depletion.