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Benjamin T. Kopp

Researcher at Nationwide Children's Hospital

Publications -  86
Citations -  7977

Benjamin T. Kopp is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Cystic fibrosis & Medicine. The author has an hindex of 20, co-authored 73 publications receiving 6327 citations. Previous affiliations of Benjamin T. Kopp include The Research Institute at Nationwide Children's Hospital & University of Iowa.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.

TL;DR: It is shown for the first time that in wild-type macrophages, many B. cepacia reside in autophagosomes that fuse with lysosomes at later stages of infection, and it is demonstrated that if efficiently activated, autophagy can control B. Cepacia infection and ameliorate the associated inflammation.
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Respiratory syncytial virus: current and emerging treatment options

TL;DR: There is a clear need for novel RSV preventative and therapeutic strategies that may help prevent or decrease the severity of RSV infections in infants and children.
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Aging is associated with hypermethylation of autophagy genes in macrophages

TL;DR: This study builds a foundation for the development of novel therapeutics aimed to improve autophagy in the elderly population and suggests a role for DNMT2 in DNA methylation activities.