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Diego Ruano

Researcher at University of Seville

Publications -  60
Citations -  9428

Diego Ruano is an academic researcher from University of Seville. The author has contributed to research in topics: GABAA receptor & Protein subunit. The author has an hindex of 31, co-authored 60 publications receiving 7902 citations. Previous affiliations of Diego Ruano include Centre national de la recherche scientifique & Spanish National Research Council.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

Sebastian Jimenez, +9 more
- 05 Nov 2008 - 
TL;DR: Evidence is shown of a switch in the activated microglia phenotype from alternative, at the beginning of Aβ pathology, to a classical at advanced stage of the disease in this model, induced by the age-dependent accumulation of extracellular soluble Aβ oligomers.
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Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1 × APP transgenic model of Alzheimer's disease

Blanca Ramos, +11 more
- 01 Nov 2006 - 
TL;DR: An extensive, selective and early neurodegeneration of the dendritic inhibitory interneurons in the hippocampus of a transgenic PS1xAPP AD model is reported and might represent an early hippocampal neuropathology.
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Cellular environment facilitates protein accumulation in aged rat hippocampus

M. Paz Gavilán, +6 more
- 01 Jul 2006 - 
TL;DR: It is demonstrated that unfolding protein response (UPR) is not correctly activated in aged rat hippocampus, and the up-regulation of apoptotic pathway mediators is increased in aged rats, suggesting the existence of age-related deficits in the systems involved in the defense against unfolded proteins.