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Michael J. Ragusa

Researcher at Dartmouth College

Publications -  41
Citations -  8419

Michael J. Ragusa is an academic researcher from Dartmouth College. The author has contributed to research in topics: Autophagy & Protein structure. The author has an hindex of 19, co-authored 36 publications receiving 6875 citations. Previous affiliations of Michael J. Ragusa include National Institutes of Health & California Institute for Quantitative Biosciences.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The extended PP1 toolkit: designed to create specificity

TL;DR: Novel insights offer perspectives for the therapeutic targeting of PP1 by interfering with the binding of PIPs or substrates.
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Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

TL;DR: The data support a crucial role for MEF2C in programming early neuronal differentiation and proper distribution within the layers of the neocortex, and show that conditional knockout of Mef2c in nestin-expressing neural stem/progenitor cells (NSCs) impaired neuronal differentiation in vivo.
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Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

TL;DR: The C-terminal EAT domain of Atg1 was shown to sense membrane curvature, dimerize, and tether lipid vesicles, which suggest a structural mechanism for the organization of AtG9 vesicle into the early phagophore.