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Esther Wong

Researcher at National University of Singapore

Publications -  41
Citations -  12447

Esther Wong is an academic researcher from National University of Singapore. The author has contributed to research in topics: Autophagy & Chaperone-mediated autophagy. The author has an hindex of 25, co-authored 41 publications receiving 10589 citations. Previous affiliations of Esther Wong include University Health System & Yeshiva University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Autophagy gone awry in neurodegenerative diseases

Esther Wong, +1 more
- 01 Jul 2010 - 
TL;DR: Examples of different types of autophagic dysfunction described in common neurodegenerative disorders are presented and the prospect of exploring some of the recently identified Autophagic variants and the interactions among autphagic and non-autophagic proteolytic systems as possible future therapeutic targets are discussed.
Journal ArticleDOI

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

Marta Martinez-Vicente, +12 more
- 01 May 2010 - 
TL;DR: It is proposed that inefficient engulfment of cytosolic components by autophagosomes is responsible for their slower turnover, functional decay and accumulation inside HD cells.
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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Joo-Yong Lee, +12 more
- 03 Mar 2010 - 
TL;DR: This study identifies HDAC6 and the actin cytoskeleton as critical components that define QC autophagy and uncovers a novel regulation of autophophagy at the level of Autophagosome–lysosome fusion.