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Jennifer S. Carew

Researcher at University of Arizona

Publications -  119
Citations -  19487

Jennifer S. Carew is an academic researcher from University of Arizona. The author has contributed to research in topics: Autophagy & Bortezomib. The author has an hindex of 42, co-authored 113 publications receiving 16524 citations. Previous affiliations of Jennifer S. Carew include Cleveland Clinic & University of Texas Health Science Center at San Antonio.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal Article

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

Rui-Hua Xu, +7 more
- 15 Jan 2005 - 
TL;DR: This study reports that inhibition of glycolysis severely depletes ATP in cancer cells, especially in clones of cancer cells with mitochondrial respiration defects, and leads to rapid dephosphorylation of the gly colysis-apoptosis integrating molecule BAD at Ser(112), relocalization of BAX to mitochondria, and massive cell death.
Journal ArticleDOI

Mitochondrial defects in cancer

Jennifer S. Carew, +3 more
- 09 Dec 2002 - 
TL;DR: A brief summary of the current understanding of mitochondrial genetics and biology is provided, the mtDNA alterations reported in various types of cancer are reviewed, and some perspective is offered as to the emergence of mtDNA mutations, their functional consequences in cancer development, and therapeutic implications.