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Udai Bhan Pandey

Researcher at University of Pittsburgh

Publications -  66
Citations -  11817

Udai Bhan Pandey is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Neurodegeneration & Medicine. The author has an hindex of 29, co-authored 51 publications receiving 8939 citations. Previous affiliations of Udai Bhan Pandey include Sanjay Gandhi Post Graduate Institute of Medical Sciences & University of Pennsylvania.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

TL;DR: It is shown that autophagy acts as a compensatory degradation system when the UPS is impaired in Drosophila melanogaster, and that histone deacetylase 6 (HDAC6), a microtubule-associated de acetylase that interacts with polyubiquitinated proteins, is an essential mechanistic link in this compensatory interaction.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

TL;DR: The basic biology of the fly is reviewed and models of human diseases and opportunities for therapeutic discovery for central nervous system disorders, inflammatory disorders, cardiovascular disease, cancer, and diabetes are discussed.
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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

TL;DR: This study identifies HDAC6 and the actin cytoskeleton as critical components that define QC autophagy and uncovers a novel regulation of autophophagy at the level of Autophagosome–lysosome fusion.