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Jun-Lin Guan

Researcher at University of Cincinnati Academic Health Center

Publications -  229
Citations -  41698

Jun-Lin Guan is an academic researcher from University of Cincinnati Academic Health Center. The author has contributed to research in topics: Focal adhesion & Autophagy. The author has an hindex of 80, co-authored 217 publications receiving 35364 citations. Previous affiliations of Jun-Lin Guan include Cornell University & University of Michigan.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

Chun Chi Liang, +2 more
- 01 Feb 2007 - 
TL;DR: The in vitro scratch assay is particularly suitable for studies on the effects of cell–matrix and cell–cell interactions on cell migration, mimic cell migration during wound healing in vivo and are compatible with imaging of live cells during migration to monitor intracellular events if desired.
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Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Nao Hosokawa, +13 more
- 01 Apr 2009 - 
TL;DR: A novel mammalian autophagy factor, Atg13, is reported, which forms a stable approximately 3-MDa protein complex with ULK1 and FIP200, and suggests that mTORC1 suppressesAutophagy through direct regulation of the approximately 3,MDa ULK 1-Atg13-FIP200 complex.
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Recognition of RNA N 6 -methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang, +49 more
- 23 Feb 2018 - 
TL;DR: This work reports the insulin-like growth factor 2 mRNA-binding proteins as a distinct family of m6A readers that target thousands of mRNA transcripts through recognizing the consensus GG(m6A)C sequence, and identifies IGF2BPs as an additional class of N6-methyladenosine (m 6A) reader proteins.