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Irina Petrache

Researcher at University of Colorado Denver

Publications -  210
Citations -  15814

Irina Petrache is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Ceramide & Lung. The author has an hindex of 51, co-authored 181 publications receiving 13493 citations. Previous affiliations of Irina Petrache include Veterans Health Administration & Indiana University – Purdue University Indianapolis.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

Tirumalai Rangasamy, +9 more
- 01 Nov 2004 - 
TL;DR: The responsiveness of the Nrf2 pathway may act as a major determinant of susceptibility to tobacco smoke-induced emphysema by upregulating antioxidant defenses and decreasing lung inflammation and alveolar cell apoptosis.
Journal ArticleDOI

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.

Irina Petrache, +8 more
- 24 Apr 2005 - 
TL;DR: Increased lung ceramides in individuals with smoking-induced emphysema suggests that ceramide upregulation may be a crucial pathogenic element and a promising target in this disease that currently lacks effective therapies.
Journal ArticleDOI

Pathogenesis of chronic obstructive pulmonary disease

Rubin M. Tuder, +1 more
- 01 Aug 2012 - 
TL;DR: The pathogenesis of COPD is discussed, with particular focus on emphysema, based on the concept that pulmonary injury involves stages of initiation (by exposure to cigarette smoke, pollutants, and infectious agents), progression, and consolidation.