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Zhong Chen

Researcher at Zhejiang Chinese Medical University

Publications -  354
Citations -  16048

Zhong Chen is an academic researcher from Zhejiang Chinese Medical University. The author has contributed to research in topics: Epilepsy & Histamine. The author has an hindex of 46, co-authored 300 publications receiving 12212 citations. Previous affiliations of Zhong Chen include State Administration of Traditional Chinese Medicine of the People's Republic of China & Zhejiang University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

TL;DR: Autophagy was activated in the reperfusion phase, as revealed in both mice with middle cerebral artery occlusion and oxygen-glucose deprived cortical neurons in culture, and the protective role of autophagy during reperfusions may be attributable to mitophagy-related mitochondrial clearance and inhibition of downstream apoptosis.
Posted ContentDOI

The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in human and mouse brain

TL;DR: The results reveal an outline of ACE2/Ace2 distribution in the human and mouse brain, which indicates the brain infection of SARS-CoV-2 may be capable of inducing central nervous system symptoms in coronavirus disease 2019 (COVID-19) patients.
Journal ArticleDOI

The Spatial and Cell-Type Distribution of SARS-CoV-2 Receptor ACE2 in the Human and Mouse Brains

TL;DR: In this article, the authors investigated the ACE2 expression in the brain by analyzing data from publicly available brain transcriptome databases and revealed an outline of ACE2/Ace2 distribution in the human and mouse brains, which indicates that the brain infection of SARS-CoV-2 may be capable of inducing central nervous system symptoms in coronavirus disease 2019 (COVID-19) patients.