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Tiago F. Outeiro

Researcher at University of Göttingen

Publications -  352
Citations -  24231

Tiago F. Outeiro is an academic researcher from University of Göttingen. The author has contributed to research in topics: Alpha-synuclein & Synucleinopathies. The author has an hindex of 66, co-authored 305 publications receiving 19589 citations. Previous affiliations of Tiago F. Outeiro include Newcastle University & Nova Southeastern University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease

Tiago F. Outeiro, +14 more
- 27 Jul 2007 - 
TL;DR: A potent inhibitor of sIRT2 was identified and inhibition of SIRT2 rescued α-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson's disease, suggesting a link between neurodegeneration and aging.
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Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology

Tiago F. Outeiro, +1 more
- 05 Dec 2003 - 
TL;DR: This readily manipulable system provides an opportunity to dissect the molecular pathways underlying normal alpha-synuclein biology and the pathogenic consequences of its misfolding.
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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Christian Hansen, +11 more
- 01 Feb 2011 - 
TL;DR: In vivo transfer of α-syn between host cells and grafted dopaminergic neurons in mice overexpressing human α- syn and results suggest that α- Syn propagation is a key element in the progression of Parkinson disease pathology.