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Ryan J. Schulze

Researcher at Mayo Clinic

Publications -  29
Citations -  8155

Ryan J. Schulze is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Lipid droplet & Bacterial outer membrane. The author has an hindex of 21, co-authored 28 publications receiving 6376 citations. Previous affiliations of Ryan J. Schulze include University of Kansas & University of Bristol.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The small GTPase Rab7 as a central regulator of hepatocellular lipophagy.

Barbara Schroeder, +5 more
- 01 Jun 2015 - 
TL;DR: It is demonstrated that Rab7 is indispensable for LD breakdown (“lipophagy”) in hepatocytes subjected to nutrient deprivation, while implicating the small GTPase Rab7 as a key regulatory component of this essential process.
Journal ArticleDOI

Breaking fat: The regulation and mechanisms of lipophagy

Ryan J. Schulze, +2 more
- 01 Oct 2017 - 
TL;DR: A review of recent work focusing on LDs and lipophagy as well as highlighting challenges and future directions of research as the understanding oflipophagy continues to grow and evolve is summarized.
Journal ArticleDOI

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes.

Micah B. Schott, +7 more
- 07 Oct 2019 - 
TL;DR: In hepatocytes, Schott et al. report that the lipolysis enzyme ATGL targets large LDs upstream of lipophagy, which is restricted to small LDs.