scispace - formally typeset
V

Vincent Kam Wai Wong

Researcher at Macau University of Science and Technology

Publications -  132
Citations -  9614

Vincent Kam Wai Wong is an academic researcher from Macau University of Science and Technology. The author has contributed to research in topics: Autophagy & Cancer cell. The author has an hindex of 28, co-authored 127 publications receiving 7168 citations. Previous affiliations of Vincent Kam Wai Wong include Hong Kong University of Science and Technology & Hong Kong Baptist University.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

Jin-Feng Teng, +15 more
- 13 Jan 2020 - 
TL;DR: PPVI-induced, caspase-1-mediated pyroptosis via the induction of the ROS/NF-κB/NLRP3/GSDMD signal axis in NSCLC was clarified, which further clarified the mechanism of PPVI in the inhibition ofNSCLC, and thereby provided a possibility for PPVI to serve as a novel therapeutic agent for NSclC in the future.
Journal ArticleDOI

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

Betty Yuen Kwan Law, +6 more
- 01 May 2015 - 
TL;DR: A group of natural alkaloid small-molecules that function as novel autophagic enhancers are identified, which provides novel insights into the biological functions, mechanisms and potential therapeutic values of alkaloids for the induction of autophagy.
Journal ArticleDOI

Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy.

Guan-Jun Yang, +11 more
- 01 Oct 2018 - 
TL;DR: This study designed and synthesized metal complexes bearing ligands with reported demethylase and p27 modulating activities that exhibited potent anti-tumor activity against TNBC xenografts in an in vivo mouse model and is the first metal-based KDM5A inhibitor reported in the literature.