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Demetrios G. Vavvas

Researcher at Massachusetts Eye and Ear Infirmary

Publications -  317
Citations -  15746

Demetrios G. Vavvas is an academic researcher from Massachusetts Eye and Ear Infirmary. The author has contributed to research in topics: Macular degeneration & Medicine. The author has an hindex of 45, co-authored 286 publications receiving 12588 citations. Previous affiliations of Demetrios G. Vavvas include St. Vincent's Health System & Boston Medical Center.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Malonyl-CoA, fuel sensing, and insulin resistance

Neil B. Ruderman, +3 more
- 01 Jan 1999 - 
TL;DR: The hypothesis is that by altering the cytosolic concentrations of LCFA-CoA and diacylglycerol, and secondarily the activity of one or more protein kinase C isoforms, changes in malonyl- coA provide a link between fuel metabolism and signal transduction in these cells.
Journal ArticleDOI

Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle

Demetrios G. Vavvas, +7 more
- 16 May 1997 - 
TL;DR: In this article, the authors examined the activity and properties of ACC-β, the skeletal muscle isozyme that catalyzes malonyl-CoA formation, in rat gastrocnemius-soleus muscles at rest and during contractions induced by electrical stimulation of the sciatic nerve.
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Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade.

Joseph Avruch, +6 more
- 01 Jan 2001 - 
TL;DR: The way in which work from this and other laboratories on insulin signaling led to the discovery of the mammalian MAP kinase cascade and, in turn, to the identification of unique role of the Raf kinases in RTK activation of this protein (Ser/Thr) kinases cascade is summarized.