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Stefano Santaguida

Researcher at European Institute of Oncology

Publications -  59
Citations -  11048

Stefano Santaguida is an academic researcher from European Institute of Oncology. The author has contributed to research in topics: Spindle checkpoint & Aneuploidy. The author has an hindex of 27, co-authored 49 publications receiving 9061 citations. Previous affiliations of Stefano Santaguida include Mario Negri Institute for Pharmacological Research & Massachusetts Institute of Technology.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

Claudio Ciferri, +14 more
- 02 May 2008 - 
TL;DR: An engineered "bonsai" Ndc80 complex containing a shortened rod domain but retaining the globular domains required for kinetochore localization and microtubule binding is crystallized, revealing a microtubules-binding interface containing a pair of tightly interacting calponin-homology (CH) domains with a previously unknown arrangement.
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The life and miracles of kinetochores

Stefano Santaguida, +1 more
- 02 Sep 2009 - 
TL;DR: This review discusses how the molecular organization of the four modules allows a dynamic integration of kinetochore–microtubule attachment with the prevention of chromosome segregation errors and cell‐cycle progression.
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Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

Stefano Santaguida, +4 more
- 12 Jul 2010 - 
TL;DR: Addition of reversine to dividing cells ejects Mad1 and the RZZ complex from unattached kinetochores and prevents resolution of incorrect chromosome–microtubule attachments.