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Muriel Mari

Researcher at University Medical Center Groningen

Publications -  84
Citations -  13761

Muriel Mari is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Autophagy & Endoplasmic reticulum. The author has an hindex of 38, co-authored 74 publications receiving 10797 citations. Previous affiliations of Muriel Mari include University Medical Center Utrecht & University of Michigan.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion.

TL;DR: It is shown that CQ mainly inhibits autophagy by impairing autophagosome fusion with lysosomes rather than by affecting the acidity and/or degradative activity of this organelle.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Regulation of endoplasmic reticulum turnover by selective autophagy

TL;DR: Severe disruption of Fam134b in mice causes expansion of the ER, inhibits ER turnover, sensitizes cells to stress-induced apoptotic cell death and leads to degeneration of sensory neurons, so selective ER-phagy via FAM134 proteins is indispensable for mammalian cell homeostasis and controls ER morphology and turnover in mice and humans.
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An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis.

TL;DR: A reservoir of Atg9-containing vesicles and tubules provides the initial membranes necessary for autophagophore formation in yeast.