scispace - formally typeset
J

Jiandie D. Lin

Researcher at University of Michigan

Publications -  144
Citations -  29251

Jiandie D. Lin is an academic researcher from University of Michigan. The author has contributed to research in topics: Adipose tissue & Coactivator. The author has an hindex of 52, co-authored 134 publications receiving 24555 citations. Previous affiliations of Jiandie D. Lin include Life Sciences Institute & Harvard University.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Jiandie D. Lin, +12 more
- 15 Aug 2002 - 
TL;DR: Using fibre-type-specific promoters, it is shown in cultured muscle cells that PGC-1α activates transcription in cooperation with Mef2 proteins and serves as a target for calcineurin signalling, which has been implicated in slow fibre gene expression.
Journal ArticleDOI

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao, +12 more
- 15 Jul 2008 - 
TL;DR: TEAD is revealed as a new component in the Hippo pathway playing essential roles in mediating biological functions of YAP, and is required for YAP-induced cell growth, oncogenic transformation, and epithelial-mesenchymal transition.
Journal ArticleDOI

Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

Julie St-Pierre, +13 more
- 20 Oct 2006 - 
TL;DR: Increase in PGC-1alpha levels dramatically protects neural cells in culture from oxidative-stressor-mediated death, providing a potential target for the therapeutic manipulation of these important endogenous toxins.
Journal ArticleDOI

Metabolic control through the PGC-1 family of transcription coactivators.

Jiandie D. Lin, +2 more
- 01 Jun 2005 - 
TL;DR: This work has shown that the PGC-1 coactivators play a critical role in the maintenance of glucose, lipid, and energy homeostasis and are likely involved in the pathogenic conditions such as obesity, diabetes, neurodegeneration, and cardiomyopathy.