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Sumit Sahni

Researcher at University of Sydney

Publications -  84
Citations -  9561

Sumit Sahni is an academic researcher from University of Sydney. The author has contributed to research in topics: Autophagy & Medicine. The author has an hindex of 29, co-authored 74 publications receiving 7593 citations. Previous affiliations of Sumit Sahni include Shanghai Jiao Tong University & Kolling Institute of Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.

TL;DR: Major aspects of the journey of iron from its initial cellular uptake, its modes of trafficking within cells, to an overview of its downstream utilization in the cytoplasm and within mitochondria are discussed.
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P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration.

TL;DR: Together, these studies reveal a new mechanism where Pgp-mediated lysosomal sequestration of chemotherapeutics leads to MDR that is amenable to therapeutic exploitation and can be exploited pharmacologically.
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Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling.

TL;DR: The latest advances in the understanding of melanoma progression and the major molecular pathways involved are described, including the functional role of the melanoma tumor antigen, p97/MFI2 (melanotransferrin).