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Alexander J. Whitworth

Researcher at MRC Mitochondrial Biology Unit

Publications -  97
Citations -  18858

Alexander J. Whitworth is an academic researcher from MRC Mitochondrial Biology Unit. The author has contributed to research in topics: PINK1 & Parkin. The author has an hindex of 36, co-authored 81 publications receiving 15523 citations. Previous affiliations of Alexander J. Whitworth include University of Sheffield & University of Cambridge.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants.

Jessica C. Greene, +5 more
- 01 Apr 2003 - 
TL;DR: It is indicated that the tissue-specific phenotypes observed in Drosophila parkin mutants result from mitochondrial dysfunction and raise the possibility that similar mitochondrial impairment triggers the selective cell loss observed in AR-JP.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The PINK1/Parkin pathway regulates mitochondrial morphology

Angela C. Poole, +5 more
- 05 Feb 2008 - 
TL;DR: The studies suggest that the PINK1/Parkin pathway promotes mitochondrial fission and that the loss of mitochondrial and tissue integrity in Pink1 and parkin mutants derives from reduced mitochondrial fissions.