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Elaine A. Dunlop

Researcher at Cardiff University

Publications -  30
Citations -  8736

Elaine A. Dunlop is an academic researcher from Cardiff University. The author has contributed to research in topics: mTORC1 & PI3K/AKT/mTOR pathway. The author has an hindex of 20, co-authored 29 publications receiving 7211 citations. Previous affiliations of Elaine A. Dunlop include Queen's University Belfast.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Elaine A. Dunlop, +1 more
- 01 Dec 2014 - 
TL;DR: It is clear that mTOR and autophagy are closely integrated within cells, where defects in signalling through both pathways are known to drive the onset of a range of human diseases, such as cancer and neurodegenerative disease.
Journal ArticleDOI

Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms

Elaine A. Dunlop, +1 more
- 01 Jun 2009 - 
TL;DR: This review provides an update on the most recent additions to the mTOR pathway with particular emphasis on mTORC1 signalling, and discusses the recent advances that have been made to determine the upstream mechanisms that control m TORC1 through hypoxia, energy sensing and nutrient signalling.
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mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of Action

Ghada A. Soliman, +6 more
- 12 Mar 2010 - 
TL;DR: This work re-examines the regulation of mTOR Ser-2481 autophosphorylation in vivo by studying mTORC-specific Ser(P)-2481 in m TORC1 andmTORC2, with a primary focus on mTOR C1.