Elizabeth Delorme-Axford

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: This work shows that cultured primary human placental trophoblasts are highly resistant to infection by a number of viruses and confer this resistance to nonplacental recipient cells by exosome-mediated delivery of specific microRNAs (miRNAs) to directly communicate with placental or maternal target cells and regulate their immunity to viral infections.

TL;DR: Data show that coxsackievirus B3 has evolved a mechanism to suppress host antiviral signal propagation by directly cleaving two key adaptor molecules associated with innate immune recognition.

TL;DR: Rph1 maintains autophagy at a low level in nutrient-rich conditions; upon nutrient limitation, the inhibition of its activity is a prerequisite to the induction of ATG gene transcription and Autophagy induction.