Young Hyun Yoo

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: A transgenic mouse model in which a mitochondrial-targeted form of the fluorescent reporter Keima was expressed, a coral-derived protein that exhibits both pH-dependent excitation and resistance to lysosomal proteases, is described, suggesting that the mt-Keima mouse should be a valuable resource.

TL;DR: It is proposed that AChE plays a pivotal role in the formation of apoptosome and blocked the interaction between apoptotic protease-activating factor-1 and cytochrome c.

TL;DR: The data suggest that regulation of ROS generation and autophagy can be a potential strategy for treating lung cancer that is resistant to pro-apoptotic therapeutics.