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Susana Castro-Obregón

Researcher at National Autonomous University of Mexico

Publications -  54
Citations -  9842

Susana Castro-Obregón is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Programmed cell death & Autophagy. The author has an hindex of 25, co-authored 50 publications receiving 8222 citations. Previous affiliations of Susana Castro-Obregón include University of California, San Francisco & Max Planck Society.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Coupling Endoplasmic Reticulum Stress to the Cell Death Program MECHANISM OF CASPASE ACTIVATION

TL;DR: It is proposed that any cellular insult that causes prolonged ER stress may induce apoptosis through caspase-7-mediated casp enzyme-12 activation, and the data underscore the involvement of ER and caspases associated with it in the ER stress-induced apoptotic process.
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Coupling Endoplasmic Reticulum Stress to the Cell Death Program AN Apaf-1-INDEPENDENT INTRINSIC PATHWAY

TL;DR: ER stress-induced programmed cell death defines a novel, mitochondrial and Apaf-1-independent, intrinsic apoptotic pathway, and the molecular requirements for this Apf-1 and cytochrome c-independent apoptosis pathway are defined.
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Function of reactive oxygen species during animal development: passive or active?

TL;DR: Recent data that are suggestive of specific ROS functions during development of animals, particularly mammals are reviewed.