David N. Zacks

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Paracentral acute middle maculopathy may represent a novel variant of AMN that affects the middle layers of the macula above the OPL as diagnosed with SD-OCT imaging and it is proposed that each of these lesions may be explained by occlusion of either the superficial capillary plexus or deep capillaryplexus located in the innermost and outermost portion of the INL.

TL;DR: The apoptotic photoreceptor cell death in experimental retinal detachments is associated with caspase activation, and the morphologic features associated with apoptosis are detected in attached retinas.

TL;DR: The FAS-mediated apoptosis pathway becomes activated and transcriptionally upregulated after retinal detachment, and inhibition of FAS activation can decrease caspase-9 activity.