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Shivendra V. Singh

Researcher at University of Pittsburgh

Publications -  275
Citations -  18896

Shivendra V. Singh is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Cancer cell & Apoptosis. The author has an hindex of 64, co-authored 256 publications receiving 16734 citations. Previous affiliations of Shivendra V. Singh include Mercy Medical Center (Baltimore, Maryland) & University of Texas Medical Branch.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species

Shivendra V. Singh, +12 more
- 20 May 2005 - 
TL;DR: The results of the present study indicate that SFN-induced apoptosis in prostate cancer cells is initiated by ROS generation and that both intrinsic and extrinsic caspase cascades contribute to the cell death caused by this highly promising cancer chemopreventive agent.
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Sulforaphane-induced G2/M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2-mediated Phosphorylation of Cell Division Cycle 25C

Shivendra V. Singh, +8 more
- 11 Jun 2004 - 
TL;DR: It is demonstrated that SFN treatment causes an irreversible arrest in the G2/M phase of the cell cycle, and activation of checkpoint kinase 2 (Chk2) plays a major role in irreversible G 2/M arrest by SFN.
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Sulforaphane Causes Autophagy to Inhibit Release of Cytochrome c and Apoptosis in Human Prostate Cancer Cells

Anna Herman-Antosiewicz, +2 more
- 01 Jun 2006 - 
TL;DR: It is indicated that induction of autophagy represents a defense mechanism against sulforaphane-induced apoptosis in human prostate cancer cells, the first published report to convincingly document induction ofAutophagy by an isothiocyanate class of dietary chemopreventive agent.