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Marc Germain

Researcher at Université du Québec à Trois-Rivières

Publications -  46
Citations -  10166

Marc Germain is an academic researcher from Université du Québec à Trois-Rivières. The author has contributed to research in topics: Mitochondrion & Endoplasmic reticulum. The author has an hindex of 28, co-authored 42 publications receiving 7822 citations. Previous affiliations of Marc Germain include Laval University & McGill University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Regulation of apoptosis by endoplasmic reticulum pathways

David G. Breckenridge, +4 more
- 24 Nov 2003 - 
TL;DR: The potential underlying mechanisms involved in the regulation of the mitochondrial checkpoint are reviewed and pathways for ER–mitochondrial crosstalk pertinent to a number of cell death stimuli are discussed.
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Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7.

Marc Germain, +5 more
- 01 Oct 1999 - 
TL;DR: The results strongly suggest that, in vivo, it is caspase-7 that is responsible for PARP cleavage and that poly(ADP-ribosyl)ation of PARP accelerates its proteolysis.
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Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

Mireille Khacho, +11 more
- 04 Aug 2016 - 
TL;DR: Findings reveal mitochondrial dynamics as an upstream regulator of essential mechanisms governing stem cell self-renewal and fate decisions through transcriptional programming.