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Luc Van Kaer

Researcher at Vanderbilt University

Publications -  276
Citations -  29165

Luc Van Kaer is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Natural killer T cell & Immune system. The author has an hindex of 79, co-authored 261 publications receiving 26242 citations. Previous affiliations of Luc Van Kaer include Northwestern University & Niigata University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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NKT cells: what's in a name?

Dale I. Godfrey, +4 more
- 01 Mar 2004 - 
TL;DR: This perspective article seeks to clarify which cells fall under the NKT-cell umbrella, and which might be best considered as separate.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Evidence for a differential avidity model of T cell selection in the thymus

Philip G. Ashton-Rickardt, +6 more
- 25 Feb 1994 - 
TL;DR: A critical parameter that controls the fate of a thymocyte seems to be the number of TCRs engaged with complexes of peptide and major histocompatibility complex and when this number is low, positive selection occurs, and when it is high, negative selection takes place.
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TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells.

Luc Van Kaer, +6 more
- 24 Dec 1992 - 
TL;DR: Mice with a disrupted TAP1 gene are generated using embryonic stem cell technology and show severely reduced levels of surface class I molecules, strikingly similar to those described for the TAP2 mutant cell line RMA-S.