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Claudia Manzoni

Researcher at University College London

Publications -  79
Citations -  11133

Claudia Manzoni is an academic researcher from University College London. The author has contributed to research in topics: LRRK2 & Genome-wide association study. The author has an hindex of 29, co-authored 70 publications receiving 8545 citations. Previous affiliations of Claudia Manzoni include University of Reading & UCL Institute of Neurology.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Mike A. Nalls, +248 more
- 01 Dec 2019 - 
TL;DR: These data provide the most comprehensive survey of genetic risk within Parkinson's disease to date, providing a biological context for these risk factors, and showing that a considerable genetic component of this disease remains unidentified.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein

TL;DR: It is reported that, in mice, acute intracerebroventricular injections of synthetic Aβ1–42 oligomers impaired consolidation of the long-term recognition memory, whereas mature Aβ 1–42 fibrils and freshly dissolved peptide did not, and it was confirmed that A β1– 42 oligomers interact with PrPC, with nanomolar affinity.
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Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.

TL;DR: This review cuts across the boundaries between genomics, transcriptomics and proteomics, summarizing how omics data are generated, analysed and shared and provides an overview of the current strengths and weaknesses of this global approach.