Gustavo J.S. Pereira

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: It is shown that intracellular delivery of NAADP evokes Ca2+ signals from acidic organelle formation and levels of the autophagic markers, LC3II and beclin-1, and that these signals are potentiated upon overexpression of TPCs.

TL;DR: Nutritional restriction is a promising protocol to modulate autophagy and enhance the efficacy of anticancer therapies while protecting normal cells and the possibility of using fasting as an adjuvant therapy for cancer treatment, as well as the molecular mechanisms underlying this approach.

TL;DR: The crosstalk between the endoplasmic reticulum, mitochondria, and lysosomes and their influence in apoptotic and autophagic processes is discussed.