Nava Segev

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Not only are Ypt/Rabs highly conserved, but their functions and interactions are as well, which suggest the possibility of coordination of the individual vesicular transport steps and of the protein transport machinery with other cellular processes.

TL;DR: TRAPP is a large protein complex that is required for ER-to-Golgi transport and that has properties similar to those of Ypt1 GEF, andCoprecipitation and overexpression studies suggest that TRAPP can act as a GEF for Ypt 1 and Ypt31/32 in vivo.

TL;DR: Results indicate that the Ypt31/32p GTPases are required for a step that occurs in the transGolgi compartment, between the reactions regulated by Ypt1p and Sec4p.