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Yu-Chen Hu

Researcher at National Tsing Hua University

Publications -  171
Citations -  13921

Yu-Chen Hu is an academic researcher from National Tsing Hua University. The author has contributed to research in topics: Gene delivery & Transduction (genetics). The author has an hindex of 52, co-authored 167 publications receiving 11734 citations. Previous affiliations of Yu-Chen Hu include University of Maryland, College Park & University of Maryland Biotechnology Institute.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

A graphene-based platform for induced pluripotent stem cells culture and differentiation.

TL;DR: It is reported on that G and GO can support the mouse iPSCs culture and allow for spontaneous differentiation, and implicate the potentials of graphene-based materials as a platform for iPSC culture and diverse applications.
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Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge.

TL;DR: Compared with the VLP immunization, immunization with denatured VLP and heat-inactivated EV71 elicited lower neutralization titers and conferred less effective protection to newborn mice, although they induced comparable levels of total IgG and cellular immune responses.
Journal ArticleDOI

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide.

TL;DR: It is demonstrated that GO treatment of cells simultaneously triggers autophagy and TLR4/TLR9-regulated inflammatory responses, and the Autophagy was at least partly regulated by the TLRs pathway.