Ying Yang

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Whether the survival of women with recurrent breast cancer has improved from 1974 to 2000 has improved is determined.

TL;DR: High levels of phosphorylation of Akt, mTOR, and 4E-BP1 in breast cancers are demonstrated, indicating activation of the Akt/mTOR/4E- BP1 pathway in breast cancer development and progression and a potential role for this pathway in predicting the prognosis of patients with breast cancer, especially those treated with mTOR inhibitors.

TL;DR: This review summarizes the current advances and discusses the unanswered questions in understanding the involvement of autophagy in pathogenic mechanisms of disease, primarily focusing on cancer and neurodegenerative diseases.