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Patrick Brest

Researcher at French Institute of Health and Medical Research

Publications -  96
Citations -  14957

Patrick Brest is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Cancer & Autophagy. The author has an hindex of 31, co-authored 86 publications receiving 12387 citations. Previous affiliations of Patrick Brest include University of Nice Sophia Antipolis & Centre Hospitalier Universitaire de Nice.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Human polymorphism at microRNAs and microRNA target sites.

Liuqing Yang, +168 more
- 01 Jan 2013 - 
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

Patrick Brest, +24 more
- 01 Mar 2011 - 
TL;DR: It is shown that a family of microRNAs, miR-196, is overexpressed in the inflammatory intestinal epithelia of individuals with Crohn's disease and downregulates the IRGM protective variant but not the risk-associated allele, implicating a synonymous polymorphism as a likely causal variant.