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Helin Vakifahmetoglu-Norberg

Researcher at Karolinska Institutet

Publications -  35
Citations -  8771

Helin Vakifahmetoglu-Norberg is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Autophagy & Chaperone-mediated autophagy. The author has an hindex of 17, co-authored 29 publications receiving 6887 citations. Previous affiliations of Helin Vakifahmetoglu-Norberg include Harvard University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity

Bénédicte F. Py, +3 more
- 24 Jan 2013 - 
TL;DR: It is shown that the activation of NLRP3 inflammasome is regulated by a deubiquitination mechanism, and the deubiqueitinating enzyme, BRCC3, is identified as a critical regulator ofNLRP3 activity by promoting its deubanquitination and characterizing NLRP 3 as a substrate for the cytosolic BRCC 3-containing BRISC complex.
Journal ArticleDOI

The role of mitochondria in metabolism and cell death

Helin Vakifahmetoglu-Norberg, +2 more
- 15 Jan 2017 - 
TL;DR: In this article, a review on the integration of mitochondrial metabolism and apoptotic cell death is presented, where the authors give a brief account of the integration and integration of mitochondria metabolism and cell death.
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Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim, +19 more
- 24 Mar 2015 - 
TL;DR: It is shown that necroptosis mediates oligodendrocyte degeneration induced by TNF-α and that inhibition of RIPK1 protects against oligod endodermal cell death in two animal models of MS and in culture.