Yongqiang Chen

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: An overview of the roles ROS and autophagy play in cell survival and cell death, and their importance to cancer is given.

TL;DR: This Commentary focuses on the main unresolved questions in the regulation of autophagy, such as how the Atg1 complex is activated and the function of PtdIns3K is regulated, how the ubiquitin-like conjugation systems participate in Autophagy and the mechanisms of phagophore expansion and autophagosome formation.

TL;DR: Results indicate that targeting mETC complex I and II selectively induces autophagic cell death through a ROS-mediated mechanism, and treatment of non-transformed primary mouse astrocytes with rotenone or TTFA failed to significantly increase levels of ROS or autophagy.