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Shigeomi Shimizu

Researcher at Tokyo Medical and Dental University

Publications -  186
Citations -  35941

Shigeomi Shimizu is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Apoptosis & Autophagy. The author has an hindex of 62, co-authored 179 publications receiving 32182 citations. Previous affiliations of Shigeomi Shimizu include Idun Pharmaceuticals & Osaka University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

TL;DR: The results indicate that the Bcl-2 family of proteins bind to the VDAC in order to regulate the mitochondrial membrane potential and the release of cytochrome c during apoptosis.
Journal ArticleDOI

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

TL;DR: The results indicate that the CypD-dependent mPT regulates some forms of necrotic death, but not apoptotic death, as indicated by resistance to ischaemia/reperfusion-induced cardiac injury.