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Ilya Gukovsky

Researcher at University of California, Los Angeles

Publications -  91
Citations -  11918

Ilya Gukovsky is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Pancreatitis & Acinar cell. The author has an hindex of 44, co-authored 87 publications receiving 9457 citations. Previous affiliations of Ilya Gukovsky include Russian Academy of Sciences & West Los Angeles College.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha : role in regulating cell death and pancreatitis

TL;DR: The results indicate that pancreatic acinar cells produce, release, and respond to TNFalpha, a cytokine that regulates apoptosis in both isolated pancreas and experimental pancreatitis.
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Reactive Oxygen Species Produced by NAD(P)H Oxidase Inhibit Apoptosis in Pancreatic Cancer Cells

TL;DR: The results show that growth factor-induced ROS produced by NAD(P)H oxidase (probably Nox4) protect pancreatic cancer cells from apoptosis, and may play an important role in pancreaticcancer resistance to treatment and thus represent a novel therapeutic target.
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Early NF-κB activation is associated with hormone-induced pancreatitis

TL;DR: It is shown that transcription factor nuclear factor-κB, which regulates these processes, is activated and plays a role in rat cerulein pancreatitis, and antioxidant N-acetylcysteine blocked NF-κBs activation and significantly improved parameters of pancreatitis.