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Abraham Acevedo-Arozena

Researcher at Hospital Universitario de Canarias

Publications -  43
Citations -  8002

Abraham Acevedo-Arozena is an academic researcher from Hospital Universitario de Canarias. The author has contributed to research in topics: Huntingtin & Autophagosome. The author has an hindex of 20, co-authored 41 publications receiving 5953 citations. Previous affiliations of Abraham Acevedo-Arozena include Medical Research Council.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

Ashley R. Winslow, +12 more
- 20 Sep 2010 - 
TL;DR: α-Synuclein impairs autophagosome formation and mislocalizes Atg9 by inhibiting Rab1a.
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Dynein mutations impair autophagic clearance of aggregate-prone proteins.

Brinda Ravikumar, +7 more
- 26 Jun 2005 - 
TL;DR: It is shown that mutations of the dynein machinery enhanced the toxicity of the mutation that causes Huntington disease in fly and mouse models, and loss of dyne in function resulted in premature aggregate formation by mutant huntingtin and increased levels of the autophagosome marker LC3-II.
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Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

Claudia Rose, +7 more
- 01 Jun 2010 - 
TL;DR: Rilmenidine administration attenuated the signs of disease in a HD mouse model and reduced levels of the mutant huntingtin fragment, and the data suggests that it should be considered for the treatment of HD and related conditions.