Luisa Dalla Valle

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: It is shown that the scaffold protein AMBRA1 regulates cell proliferation by facilitating the dephosphorylation and degradation of the proto-oncogene c-Myc and that, when mTOR is inhibited, it enhances PP2A activity on this specific target, thereby reducing the cell division rate.

TL;DR: Results showed that 5 μg/L BPA down-regulated oocyte maturation-promoting signals, likely through changes in the chromatin structure mediated by histone modifications, and promoted apoptosis in mature follicles, indicating that the negative effects of BPA on the female reproductive system may be due to its upstream ability to deregulate epigenetic mechanism.

TL;DR: RNA1 and RNA2 genes substitution rates do not follow a clock-like behavior thus impeding estimation of a possible origin time for Betanodavirus genus, and the molecular evolution of proteins A and CPp appeared to have evolved under strong purifying selection.