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Liang Ge

Researcher at Tsinghua University

Publications -  48
Citations -  8832

Liang Ge is an academic researcher from Tsinghua University. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 22, co-authored 40 publications receiving 7026 citations. Previous affiliations of Liang Ge include Howard Hughes Medical Institute & University of California, Berkeley.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

Liang Ge, +3 more
- 06 Aug 2013 - 
TL;DR: A systematic membrane isolation scheme is developed to identify the endoplasmic reticulum–Golgi intermediate compartment (ERGIC) as a primary membrane source both necessary and sufficient to trigger LC3 lipidation in vitro.
Journal ArticleDOI

The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

Liang Ge, +7 more
- 04 Jun 2008 - 
TL;DR: A model wherein cholesterol is internalized into cells with NPC1L1 through clathrin/AP2-mediated endocytosis and ezetimibe inhibits cholesterol absorption by blocking the internalization of NPC1 L1 is suggested.
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Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

Min Zhang, +4 more
- 02 Nov 2015 - 
TL;DR: An autophagy-regulated secretion of mature IL-1β in non-macrophage cells is reconstituted and it is found that cytoplasmic IL- 1β associates with the autophagosome and m-IL-1 β enters into the lumen of a vesicle intermediate but not into the cytopLasmic interior formed by engulfment of the Autophagic membrane.