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Isabelle Coppens

Researcher at Johns Hopkins University

Publications -  166
Citations -  19820

Isabelle Coppens is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Toxoplasma gondii & Intracellular parasite. The author has an hindex of 55, co-authored 155 publications receiving 16522 citations. Previous affiliations of Isabelle Coppens include Yale University & Université catholique de Louvain.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

Yun M. Ling, +6 more
- 04 Sep 2006 - 
TL;DR: Evidence for lysosome-mediated degradation of Toxoplasma gondii after invasion of macrophages activated in vivo is presented, outlining a series of mechanisms used by effector cells to redirect the fate of a classically nonfusogenic intracellular pathogen toward a path of immune elimination.
Journal ArticleDOI

Toxoplasma gondii Sequesters Lysosomes from Mammalian Hosts in the Vacuolar Space

Isabelle Coppens, +6 more
- 21 Apr 2006 - 
TL;DR: This work demonstrates that the parasitophorous vacuole (PV) of T. gondii accumulates material coming from the host mammalian cell via the exploitation of the host endo-lysosomal system, and identifies a unique mechanism for unidirectional transport and sequestration of host organelles.