scispace - formally typeset
P

Patric J. Jansson

Researcher at University of Sydney

Publications -  89
Citations -  11278

Patric J. Jansson is an academic researcher from University of Sydney. The author has contributed to research in topics: Cancer & Autophagy. The author has an hindex of 39, co-authored 80 publications receiving 9080 citations. Previous affiliations of Patric J. Jansson include Kolling Institute of Medical Research & Charles University in Prague.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

TL;DR: Detailed investigations of the thiosemicarbazone group of ligands have demonstrated that they are highly effective chelators that, besides RR, also target a range of other molecules including NDRG1 and top2α, all of which contribute to their anticancer effects.
Journal ArticleDOI

Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.

TL;DR: Major aspects of the journey of iron from its initial cellular uptake, its modes of trafficking within cells, to an overview of its downstream utilization in the cytoplasm and within mitochondria are discussed.
Journal ArticleDOI

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

TL;DR: The alterations in Fe metabolism in tumour cells and the systematic development of novel aroylhydrazone and thiosemicarbazone Fe chelators for cancer treatment are examined.