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Ian G. Ganley

Researcher at University of Dundee

Publications -  84
Citations -  17806

Ian G. Ganley is an academic researcher from University of Dundee. The author has contributed to research in topics: Mitophagy & Autophagy. The author has an hindex of 35, co-authored 71 publications receiving 13985 citations. Previous affiliations of Ian G. Ganley include Stanford University & Babraham Institute.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Ian G. Ganley, +5 more
- 01 May 2009 - 
TL;DR: It is demonstrated by using both cellular experiments and a de novo in vitro reconstituted reaction that FIP200 and ATG13 can enhance ULK1 kinase activity individually but both are required for maximal stimulation, indicating that the ULK 1·ATG13·FIP200 complex acts as a node for integrating incoming autophagy signals into autophagosome biogenesis.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

The mammalian ULK1 complex and autophagy initiation.

Maria Zachari, +1 more
- 12 Dec 2017 - 
TL;DR: The complex pattern of upstream pathways that converge on ULK1 suggests that this complex acts as a node, converting multiple signals into autophagosome formation, and what happens downstream, once the ULK 1 complex becomes activated.