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Darius Ebrahimi-Fakhari

Researcher at Boston Children's Hospital

Publications -  97
Citations -  9887

Darius Ebrahimi-Fakhari is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Hereditary spastic paraplegia. The author has an hindex of 29, co-authored 75 publications receiving 7806 citations. Previous affiliations of Darius Ebrahimi-Fakhari include Heidelberg University & Harvard University.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Distinct roles in vivo for the Ubiquitin-Proteasome system and the Autophagy-Lysosomal Pathway in the Degradation of α-Synuclein

Darius Ebrahimi-Fakhari, +7 more
- 12 Oct 2011 - 
TL;DR: A novel link between the UPS, the ALP, and α-synuclein pathology is provided and may have important implications for future therapeutics targeting degradation pathways.
Journal ArticleDOI

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation

Jonathan O. Lipton, +11 more
- 21 May 2015 - 
TL;DR: The role of the circadian clock to the regulation of protein synthesis is expanded and the key circadian transcription factor BMAL1 is a translation factor that links circadian timing and the mTOR signaling pathway.
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Protein degradation pathways in Parkinson's disease: curse or blessing.

Darius Ebrahimi-Fakhari, +5 more
- 29 Jun 2012 - 
TL;DR: The role of protein degradation pathways in Parkinson’s disease is reviewed and elaborate on the different contributions of the UPS and the ALP to the clearance of altered proteins, as well as examining the interplay between different degradation pathways.