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Ángela M. Valverde

Researcher at Spanish National Research Council

Publications -  174
Citations -  13149

Ángela M. Valverde is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Insulin receptor & Insulin. The author has an hindex of 44, co-authored 154 publications receiving 10665 citations. Previous affiliations of Ángela M. Valverde include Complutense University of Madrid & Hospital Universitario La Paz.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

Águeda González-Rodríguez, +15 more
- 01 Apr 2014 - 
TL;DR: The results demonstrated that the autophagic flux is impaired in the liver from both NAFLD patients and murine models ofNAFLD, as well as in lipid-overloaded human hepatocytes, and it could be due to elevated ER stress leading to apoptosis.
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Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

Antonio Cuadrado, +15 more
- 01 Apr 2018 - 
TL;DR: NRF2 represents one of the first targets fully embraced by classic and systems medicine approaches to facilitate both drug development and drug repurposing by focusing on a set of disease phenotypes that appear to be mechanistically linked.
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Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

Ana Ortega-Molina, +14 more
- 07 Mar 2012 - 
TL;DR: A role of Pten is uncovered in promoting energy expenditure, thus decreasing nutrient storage and its associated damage, and a synthetic PI3K inhibitor also increases energy expenditure and hyperactivates the BAT in mice.