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Ekihiro Seki

Researcher at Cedars-Sinai Medical Center

Publications -  172
Citations -  25374

Ekihiro Seki is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Hepatic stellate cell & Liver injury. The author has an hindex of 64, co-authored 156 publications receiving 20784 citations. Previous affiliations of Ekihiro Seki include University of California, Los Angeles & Hyogo College of Medicine.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

TLR4 enhances TGF-beta signaling and hepatic fibrosis.

Ekihiro Seki, +8 more
- 01 Nov 2007 - 
TL;DR: Modulation of TGF-β signaling by a TLR4-MyD88–NF-κB axis provides a novel link between proinflammatory and profibrogenic signals.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhenyu Zhong, +19 more
- 25 Feb 2016 - 
TL;DR: The "NF-κB-p62-mitophagy" pathway is a macrophage-intrinsic regulatory loop through which NF-κBs restrains its own inflammation-promoting activity and orchestrates a self-limiting host response that maintains homeostasis and favors tissue repair.
Journal ArticleDOI

Hepatic inflammation and fibrosis: Functional links and key pathways

Ekihiro Seki, +1 more
- 01 Mar 2015 - 
TL;DR: Mechanisms that link inflammation with the development of liver fibrosis are reviewed, focusing on the role of inflammatory mediators in hepatic stellate cell (HSC) activation and HSC survival during fibrogenesis and fibrosis regression.