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Betty Yuen Kwan Law

Researcher at Macau University of Science and Technology

Publications -  115
Citations -  9029

Betty Yuen Kwan Law is an academic researcher from Macau University of Science and Technology. The author has contributed to research in topics: Autophagy & Medicine. The author has an hindex of 24, co-authored 84 publications receiving 6578 citations. Previous affiliations of Betty Yuen Kwan Law include University of Hong Kong.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

TL;DR: PPVI-induced, caspase-1-mediated pyroptosis via the induction of the ROS/NF-κB/NLRP3/GSDMD signal axis in NSCLC was clarified, which further clarified the mechanism of PPVI in the inhibition ofNSCLC, and thereby provided a possibility for PPVI to serve as a novel therapeutic agent for NSclC in the future.
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Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

TL;DR: A group of natural alkaloid small-molecules that function as novel autophagic enhancers are identified, which provides novel insights into the biological functions, mechanisms and potential therapeutic values of alkaloids for the induction of autophagy.
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Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

TL;DR: Alisol B induced calcium mobilization from internal stores, leading to autophagy through the activation of the CaMKK-AMPK-mammalian target of rapamycin pathway, which induces endoplasmic reticulum stress and unfolded protein responses in alisol B–treated cells,leading to apoptotic cell death.