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Guido Lenz

Researcher at Universidade Federal do Rio Grande do Sul

Publications -  139
Citations -  10795

Guido Lenz is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Glioma & Autophagy. The author has an hindex of 39, co-authored 125 publications receiving 8838 citations. Previous affiliations of Guido Lenz include Pontifícia Universidade Católica de Minas Gerais & Harvard University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Ratiometric analysis of Acridine Orange staining in the study of acidic organelles and autophagy.

TL;DR: The photochemical basis of Acridine Orange (AO) is described and its usefulness as a probe for autophagy quantification is found and it is found that considering the red-to-green fluorescence intensity ratio of AO gives the best correlation with other autophagic assays.
Journal ArticleDOI

Autophagy and genomic integrity

TL;DR: A hypothetical model of the role played by autophagy in dictating cell fate after genotoxic stress is presented and the importance of this crosstalk in cancer and neurodegeneration is presented in an integrated fashion.
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Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells

TL;DR: The crosstalk among autophagy, cell cycle and apoptosis, together with the biology of gCSCs, has to be considered in tailoring pharmacological interventions aimed to reduce glioma growth using compounds with multiple targets such as Rsv.