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Akitsugu Yamamoto

Researcher at Nagahama Institute of Bio-Science and Technology

Publications -  259
Citations -  46780

Akitsugu Yamamoto is an academic researcher from Nagahama Institute of Bio-Science and Technology. The author has contributed to research in topics: Endoplasmic reticulum & Golgi apparatus. The author has an hindex of 80, co-authored 259 publications receiving 42710 citations. Previous affiliations of Akitsugu Yamamoto include Kansai Medical University & Ritsumeikan University.

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Yukiko Kabeya, +13 more
- 01 Nov 2000 - 
TL;DR: It is demonstrated that the rat microtubule‐associated protein 1 light chain 3 (LC3), a homologue of Apg8p essential for autophagy in yeast, is associated to the autophagosome membranes after processing.
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Taichi Hara, +12 more
- 15 Jun 2006 - 
TL;DR: The results suggest that the continuous clearance of diffuse cytosolic proteins through basal autophagy is important for preventing the accumulation of abnormal proteins, which can disrupt neural function and ultimately lead to neurodegeneration.
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The role of autophagy during the early neonatal starvation period

Akiko Kuma, +11 more
- 23 Dec 2004 - 
TL;DR: The results suggest that the production of amino acids by autophagic degradation of ‘self’ proteins, which allows for the maintenance of energy homeostasis, is important for survival during neonatal starvation.
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In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Noboru Mizushima, +6 more
- 29 Dec 2003 - 
TL;DR: The results suggest that the regulation of autophagy is organ dependent and the role of Aut7/Apg8 is not restricted to the starvation response, and this transgenic mouse model is a useful tool to study mammalian autophagic regulation.